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Feb 
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2025
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CRC 1530 Symposium
Friday
, 
February 
21
 - 
Saturday
, 
February 
22
, 
2025
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Towards the Discovery and Targeting of Novel Pathways in Lymphoma

We are thrilled to announce the first symposium of the Collaborative Research Center 1530 (CRC 1530), the aim of which is to share the latest developments in the biology and therapy of lymphoma. The program features an international panel of excellent speakers who will present cutting-edge advances in lymphoma and inflammation research - with the aim of identifying novel therapeutic strategies for lymphoma patients and accelerating the translation of major findings into clinical application.


The symposium will take place 21-22 February 2025 in person on the campus of the University Hospital of Cologne. We are looking forward to welcoming 200 researchers, from graduate students to research group leaders, who will be able to engage in stimulating scientific discussions. 

About us

The Collaborative Research Center 1530 has been designed to establish a translational research platform of excellence for clinicians and scientists with a demonstrated track record in researching B cell malignancies or the inflammatory processes involved in lymphoma.


Our primary goal is to leverage synergies to uncover pathomechanisms and identify innovative therapeutic strategies that extend beyond the lymphoma cell-autonomous level. We aim to foster close collaborations with research partners at universities in Cologne, Essen, Frankfurt, Berlin, and Heidelberg, as well as with major German lymphoma and leukemia study groups, to facilitate the rapid translation of significant findings into clinical trials.


Visit our website to learn more about our research projects.

Speakers

Stefan Alig, MD

University Hospital Essen, Germany


Othman Al-Sawaf, MD

University Hospital of Cologne, Germany


Katarzyna Bozek, PhD

University of Cologne, Germany

.

Kerstin Brinkmann, PhD

WEHI, Melbourne, Australia

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Jan Burger, MD PhD

MD Anderson Cancer Center, Houston, USA

Descriptive text about the speaker goes here.

Stefano Casola, PhD

IFOM, Milan, Italy

Sands heads up a world-class team of 120, and leads digital capability and integration for a suite of 50+ corporate clients.

Silvia Deaglio, MD PhD

University of Turin, Italy

Nguyen covers mobile news and trends for Ad Market Magazine. Her work has also appeared in The New York Times, and Wired.com.

Sascha Dietrich, MD

University of Düsseldorf, Germany

Mobile Arts conducts quantitative and qualitative research on mobile habits, market trends, and user needs across the globe.

Barbara Eichhorst, MD

University Hospital of Cologne, Germany

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Eric Eldering, PhD

Amsterdam UMC, Netherlands

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Ana García-Sáez, PhD

Max Planck Institute of Biophysics, Frankfurt, Germany

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Sylvia Hartmann, MD

University of Duisburg-Essen, Germany

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David C. Huang, PhD

WEHI, Melbourne, Australia

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Hamid Kashkar, PhD

University of Cologne, Germany

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Emre Kocakavuk, MD PhD

University Hospital Essen, Germany

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Thomas Oellerich, MD

Goethe University, Frankfurt, Germany

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Laura Pasqualucci, MD

Columbia University, NYC, USA

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Ingo Ringshausen, MD

UCL Cancer Center, London, UK

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Philipp Schommers, MD PhD

University Hospital of Cologne, Germany

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Anna Schuh, MD

University of Oxford, UK

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Roland Schwarz, PhD

Institute for Computational Cancer Biology, Cologne, Germany

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Martina Seiffert, PhD 

German Cancer Research Center, Heidelberg, Germany

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Andreas Strasser, PhD

WEHI, Melbourne, Australia

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Friday, 21 February 2025 

09:00 - 09:15 AM

Opening Address

 Michael Hallek

09:15 – 10:45 AM

Session I - Pathogenesis and Diagnosis 


Chair: Barbara Eichhorst / Ralf Küppers

 

Stefan Alig, Noninvasive profiling of B-cell lymphomas


Anna Schuh, Early Identification of patients with MBL or Stage A CLL at high risk of progression to needing treatment


Thomas Oellerich, Pathogenesis and Clinical Relevance of DLBCL Proteogenotypes

10:45 - 11:15

Coffee Break


11:15 - 12:15 PM

Session II - Therapy and Translation


Chair: Kirsten Fischer / Gianmaria Liccardi

David C. Huang, Fine tuning the response of leukemic cells to BCL2 inhibitor therapy

 

Eric Eldering, Metabolic reprogramming in CLL: the T and B cell perspective


12:15 – 1:15 PM

Lunch


1:15 – 2:45 PM

Session II - Therapy and Translation



 Philipp Schommers, Advancing Multispecific Antibody Strategies for Immune-Mediated Lymphoma Elimination

 

Andreas Strasser, How to boost the impact of BH3 mimetic drugs for therapy of haematological cancers


Barbara Eichhorst, Concepts of Translation for Lymphoma

2:45 -  3:15 PM

Coffee break 


3:15 – 06:00 PM

Session III - Tumor Microenvironment and Immunity


Chair: Ralf Küppers / Hien Nguyen

Stefano Casola, Revisiting B cell receptor function in lymphomagenesis unveils the origin of MYC-BCL2 Double-Hit lymphomas


Silvia Deaglio, NOTCH1 and CLL: how genetic mutations shape microenvironmental interactions and metabolic adaptation


Martina Seiffert, Limitations of T cell-centered immunotherapy in B-cell malignancies and how to overcome them

4:45 - 5:00 PM

Break 


5:00 - 6:00  PM

Session III - Tumor Microenvironment and Immunity

 Ingo Ringshausen, Oncogenes and TME-skewing in B cell lymphoma: A cause and effect dilemma?


Jan Burger, CLL Microenvironment: connecting CLL cells and T cells via BCR signaling and chemokine loops

6:00 - 7:00 PM

Reception and Networking


07:30 PM

Speakers' Dinner 


Saturday, 22 February 2025

9:00 – 11:00 AM

Session VI - Computational Biology


Chair: Nima Abedpour / Michal Schweiger

Katarzyna Bozek, Quantitative insights into DLBCL morphology from patient biopsy images


Emre Kocakavuk, Longitudinal analysis of cancer genomes


Roland Schwarz, From Data to Destiny: AI’s Role in Cancer Evolution


Othman Al-Sawaf, Integrated Modelling of Chronic Lymphocytic Leukemia

11:00 - 11:30 AM

Coffee Break


11:30 AM - 1:00 PM

Session VI - Multimodal Omics Approaches


Chair: Reinhard Büttner / Björn Chapuy

Laura Pasqualucci, Hijacking super-enhancer networks by genetic lesions in Diffuse Large B cell Lymphoma


Sascha Dietrich, Multimodal Spatial Profiling of Lymph Node Microenvironment: Insights for Therapy


Sylvia Hartmann, Lymphocytes on the Move - their Choreography for Life

01:00 - 1:45 PM

Lunch


1:45 - 3:15 PM

Session VII - Cell Death and Inflammation

 

Chair: Christian Reinhardt / Henning Walczak





Keynote

Hamid Kashkar, The death and life of B cells during the process of lymphomagenesis

 

Kerstin Brinkmann, MCL-1 in Action: Unveiling Its Dual Roles in Cell Death and Metabolism for Cancer Therapy

 

Ana García-Sáez, Mitochondrial pores in apoptosis

3:15 PM

Closing Remarks 


Registration

There are no attendance fees, but registration is mandatory - we encourage you to register early as places are capped. Refreshments and lunch are included. Kindly note that registration is binding. 


Do not miss this exciting opportunity to network and discuss science with stellar researchers in lymphoma! Scroll to the top or bottom to register. 


The symposium takes place at the Center of Integrated Oncology (CIO), building 70, which is located on the campus of the University Hospital in Köln-Lindenthal. Scientific sessions will be held in room 3+4 on the ground floor of the CIO.  Access to the main entrance is from Joseph-Stelzmann-Straße.


There are very few parking facilities, we recommend travelling by public transport.

Tram stops:

- "Lindenburg", line 9, south of campus

- "Gleueler Str./Gürtel", line 13, west of campus

Bus stop:

- "Geibelstr.", line 146, north of campus 


 

About us

The Collaborative Research Center 1530 has been designed to establish a translational research platform of excellence for clinicians and scientists with a demonstrated track record in researching B cell malignancies or the inflammatory processes involved in lymphoma.


Our primary goal is to leverage synergies to uncover pathomechanisms and identify innovative therapeutic strategies that extend beyond the lymphoma cell-autonomous level. We aim to foster close collaborations with research partners at universities in Cologne, Essen, Frankfurt, Berlin, and Heidelberg, as well as with major German lymphoma and leukemia study groups, to facilitate the rapid translation of significant findings into clinical trials.

Accommodation 

Accommodation is not included in the registration and needs to be self-organized. We have reserved a room block for participants at the Ameron Regent Hotel from February 20-22, 2025; the hotel is 15 minutes away by public transport to the conference venue. The room block is available until January 20, 2025. 

Standard single room available for EUR 155.00

Standard double room available for EUR 175.00, incl. breakfast each. Please book your stay via the following link:  https://onepagebooking.com/ameronregent/allotments/15724?allotmentcode=CRC1530&lang=en 


or via phone at +49-(0) 221 54990
or via  email: reservation@hotelregent.de 

by using the keyword "CRC1530"


AMERON Köln Hotel Regent, Melatengürtel 15, 50933 Köln
https://www.ameroncollection.com/de/koeln-hotel-regent 

See you in

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